How do tumors make ends meet?
作者信息
Lengauer C
机构信息
The Johns Hopkins Oncology Center, Baltimore, MD 21231, USA.
出版信息
Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12331-3. doi: 10.1073/pnas.231485898.
Abstract
摘要
相似文献
1
How do tumors make ends meet?肿瘤是如何维持生存的？
Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12331-3. doi: 10.1073/pnas.231485898.
2
Chromosome rearrangements resulting from telomere dysfunction and their role in cancer.端粒功能障碍导致的染色体重排及其在癌症中的作用。
Bioessays. 2004 Nov;26(11):1164-74. doi: 10.1002/bies.20125.
3
The number of dysfunctional telomeres in a cell: one amplifies; more than one translocate.细胞中功能失调的端粒数量：一个会扩增；不止一个会易位。
Cytogenet Genome Res. 2008;122(3-4):315-25. doi: 10.1159/000167818. Epub 2009 Jan 30.
4
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin.入不敷出的新方式：端粒酶、DNA损伤蛋白与异染色质。
Oncogene. 2002 Jan 21;21(4):553-63. doi: 10.1038/sj.onc.1205082.
5
Long-read sequencing and de novo genome assemblies reveal complex chromosome end structures caused by telomere dysfunction at the single nucleotide level.长读测序和从头基因组组装揭示了复杂的染色体末端结构，这些结构是由单个核苷酸水平上的端粒功能障碍引起的。
Nucleic Acids Res. 2021 Apr 6;49(6):3338-3353. doi: 10.1093/nar/gkab141.
6
ZNF365 promotes stability of fragile sites and telomeres.ZNF365 促进脆性位点和端粒的稳定性。
Cancer Discov. 2013 Jul;3(7):798-811. doi: 10.1158/2159-8290.CD-12-0536. Epub 2013 Jun 17.
7
[Chromosome rearrangement involving telomeres in cancers].[癌症中涉及端粒的染色体重排]
Nihon Rinsho. 1998 May;56(5):1115-20.
8
The involvement of telomeric sequences in chromosomal aberrations.端粒序列在染色体畸变中的作用。
Mutat Res. 1996 Nov;366(2):129-35. doi: 10.1016/s0165-1110(96)90033-0.
9
Molecular targets and mechanisms in formation of chromosomal aberrations: contributions of Soviet scientists.
Cytogenet Genome Res. 2004;104(1-4):56-64. doi: 10.1159/000077466.
10
Translocation breakpoint mapping and sequence analysis in three monosomy 1p36 subjects with der(1)t(1;1)(p36;q44) suggest mechanisms for telomere capture in stabilizing de novo terminal rearrangements.对三名患有der(1)t(1;1)(p36;q44)的1p36单体综合征患者进行易位断点定位和序列分析，揭示了端粒捕获在稳定新生末端重排中的机制。
Hum Genet. 2004 Jan;114(2):198-206. doi: 10.1007/s00439-003-1029-y. Epub 2003 Oct 25.
引用本文的文献
1
Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia.端粒缩短在胰腺上皮内瘤变中几乎普遍存在。
Am J Pathol. 2002 Nov;161(5):1541-7. doi: 10.1016/S0002-9440(10)64432-X.
2
Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea.由亚硝基甲基脲引发的中国仓鼠细胞在肿瘤转化不同阶段的特定染色体异常。
Proc Natl Acad Sci U S A. 2002 May 14;99(10):6778-83. doi: 10.1073/pnas.251670699. Epub 2002 May 7.
本文引用的文献
1
The Stability of Broken Ends of Chromosomes in Zea Mays.玉米染色体断头的稳定性
Genetics. 1941 Mar;26(2):234-82. doi: 10.1093/genetics/26.2.234.
2
The Production of Homozygous Deficient Tissues with Mutant Characteristics by Means of the Aberrant Mitotic Behavior of Ring-Shaped Chromosomes.通过环状染色体的异常有丝分裂行为产生具有突变特征的纯合缺陷组织。
Genetics. 1938 Jul;23(4):315-76. doi: 10.1093/genetics/23.4.315.
3
A Correlation of Ring-Shaped Chromosomes with Variegation in Zea Mays.玉米中环形染色体与斑驳现象的相关性
Proc Natl Acad Sci U S A. 1932 Dec;18(12):677-81. doi: 10.1073/pnas.18.12.677.
4
Chromosome studies on normal and leukemic human leukocytes.对正常和白血病人类白细胞的染色体研究。
J Natl Cancer Inst. 1960 Jul;25:85-109.
5
Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors.端粒功能障碍引发人类恶性肿瘤中广泛的DNA片段化以及复杂染色体异常的演变。
Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12683-8. doi: 10.1073/pnas.211357798. Epub 2001 Oct 2.
6
Telomere dysfunction increases mutation rate and genomic instability.端粒功能障碍会增加突变率和基因组不稳定性。
Cell. 2001 Aug 10;106(3):275-86. doi: 10.1016/s0092-8674(01)00457-3.
7
Mitotic kinases as regulators of cell division and its checkpoints.有丝分裂激酶作为细胞分裂及其检查点的调节因子。
Nat Rev Mol Cell Biol. 2001 Jan;2(1):21-32. doi: 10.1038/35048096.
8
Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse.
Semin Cancer Biol. 2001 Jun;11(3):227-39. doi: 10.1006/scbi.2000.0374.
9
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans.端粒功能障碍与小鼠和人类肠道癌的演变
Nat Genet. 2001 Jun;28(2):155-9. doi: 10.1038/88871.
10
Securin is required for chromosomal stability in human cells.分离酶抑制剂对于人类细胞中的染色体稳定性是必需的。
Cell. 2001 May 18;105(4):445-57. doi: 10.1016/s0092-8674(01)00340-3.
Zotero 插件