Woolf S K, Gross R H
Department of Orthopaedic Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
J Pediatr Orthop. 2001 Nov-Dec;21(6):767-71.
Since current bone procurement and processing standards have been adopted, published studies have consistently shown that the risk of disease transmission from allograft is small. The purpose of this study was to evaluate allograft use and opinions regarding allograft safety during spinal deformity surgery. A postal survey was sent to 151 pediatric orthopaedists chosen from a cross-referenced listing of active members of both the Scoliosis Research Society and the Pediatric Orthopaedic Society of North America. The survey consisted of six questions covering allograft use during idiopathic and neuromuscular scoliosis cases, concerns about disease transmission, preoperative counseling, concerns about providers, and evaluation of clinical results. The response rate was 80%. Allograft bone use was reported by 96% of those responding for neuromuscular cases and by 62% for idiopathic cases. Infection (68%) and pseudoarthrosis (26%) were the most common topics mentioned among the 41% who addressed potential risks. Variation was found in surgeons' perceptions regarding the safety and efficacy of allograft for scoliosis surgery.
自从采用了当前的骨采集和处理标准以来,已发表的研究一直表明,同种异体移植疾病传播的风险很小。本研究的目的是评估脊柱畸形手术中同种异体移植的使用情况以及对同种异体移植安全性的看法。向从脊柱侧弯研究协会和北美小儿骨科学会活跃成员交叉索引列表中选出的151名小儿骨科医生发送了邮政调查问卷。该调查包括六个问题,涵盖特发性和神经肌肉性脊柱侧弯病例中的同种异体移植使用情况、对疾病传播的担忧、术前咨询、对供应商的担忧以及临床结果评估。回复率为80%。96%的神经肌肉病例受访者和62%的特发性病例受访者报告使用了同种异体骨。在提及潜在风险的41%的受访者中,感染(68%)和假关节(26%)是最常提到的话题。发现外科医生对同种异体移植用于脊柱侧弯手术的安全性和有效性的看法存在差异。