1-β-D-阿拉伯呋喃糖基胞嘧啶诱导的染色单体断裂：DNA合成抑制的作用
1-beta-D-arabinofuranosylcytosine-induced chromatid breakage: effect of inhibition of DNA synthesis.
作者信息
Benedict W F, Rucker N, Karon M
出版信息
J Natl Cancer Inst. 1975 Feb;54(2):431-3.
PMID:1167597
Abstract
The frequency of chromatid breakage induced by 1-beta-D-arabinofuranosylcytosine was decreased when hamster cell fibroblasts were treated with chemical agents that interferred with DNA synthesis immediately before addition of the analog. This phenomenon occurred in both the S and G2 phases of the cell cycle.
摘要
当仓鼠细胞成纤维细胞在添加类似物之前立即用干扰DNA合成的化学试剂处理时，1-β-D-阿拉伯呋喃糖基胞嘧啶诱导的染色单体断裂频率降低。这种现象发生在细胞周期的S期和G2期。
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