Olsson H, Zackrisson B
Department of Clinical Pathology, Borås Central Hospital, Sweden.
Scand J Urol Nephrol. 2001 Sep;35(4):280-2. doi: 10.1080/003655901750425846.
To evaluate the ImmunoCyt test--a urine-bound test for the detection of malignant transitional cells.
ImmunoCyt was compared with the standard investigation at our hospital for bladder cancer--cystoscopy, cytological examination of bladder wash material and, if necessary, a histological examination. A voided urine sample was collected before cystoscopy. We investigated 121 patients; seven specimens could not be evaluated.
Thirty-one of the 114 patients had a histologically proven urinary bladder carcinoma. All 31 cases were positive in the ImmunoCyt test. Twenty-six of the 83 negative cases were ImmunoCyt positive. The sensitivity was 100% and the specificity was 68.7%.
ImmunoCyt is easily applicable in a small laboratory and has high sensitivity and acceptable specificity.
评估免疫细胞检测法——一种用于检测恶性移行细胞的尿液检测方法。
将免疫细胞检测法与我院膀胱癌的标准检查方法——膀胱镜检查、膀胱冲洗液细胞学检查以及必要时的组织学检查进行比较。在膀胱镜检查前收集一份晨尿样本。我们对121例患者进行了研究；7份标本无法进行评估。
114例患者中有31例经组织学证实患有膀胱癌。所有31例在免疫细胞检测中均为阳性。83例阴性病例中有26例免疫细胞检测呈阳性。敏感性为100%，特异性为68.7%。
免疫细胞检测法易于在小型实验室应用，具有高敏感性和可接受的特异性。
