Jenzer G, Mumenthaler M, Ludin H P, Robert F
Neurology. 1975 Feb;25(2):150-3. doi: 10.1212/wnl.25.2.150.
Nine cases of botulism B with preponderant effects upon cholinergic autonomic innervation are presented. Blurred vision and dry mouth were constant symptoms. Impairment of salivary and lacrimal secretion were detectable for months. In the absence of clinical signs, electromyographic studies did not reveal neuromuscular involvement. Administration of antitoxin in the late course of such cases is not recommended, but guanidine can be used. Doubt is cast upon a new clinical entity called "acute autonomic neuropathy."
本文报告了9例主要影响胆碱能自主神经支配的B型肉毒中毒病例。视力模糊和口干是常见症状。唾液和泪液分泌受损可持续数月。在没有临床体征的情况下,肌电图检查未发现神经肌肉受累。不建议在此类病例的后期使用抗毒素,但可使用胍。对一种名为“急性自主神经病变”的新临床实体提出了质疑。