Effect of bacterial polysaccharide on the number of antibody-producing cells in the spleen of irradiated and unirradiated mice.

The effect of bacterial polysaccharide on the number of spleen cells producing antibodies against sheep's red cells was investigated in irradiated and unirradiated mice. The polysaccharide increased the number of antibody-producing cells both in lethally irradiated (psi rays) and in unirradiated mice, unimmunized with sheep's red cells. This increase was connected with the stimulation of proliferative processes in the recipient by the polysaccharide.