Collins J
Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.
Semin Reprod Med. 2001 Sep;19(3):279-89. doi: 10.1055/s-2001-18047.
In vitro fertilization (IVF) is an effective but underutilized treatment for long-standing infertility. The median projected cost per IVF cycle in 2001 in the United States would be $9226 and $3531 in 25 other countries, based on previously published estimates. The cost per delivery arising from IVF cycles in 2001 in the United States would average $56,419, and $20,522 in eight other countries, based on previously published estimates. The cost-effectiveness of IVF has not been proven in three randomized controlled trials, but these trials are difficult to design and implement. Multiple gestation births significantly increase the cost of IVF treatment. IVF multiple births cost 36% more than the IVF cycles that gave rise to the multiple births. The uptake of IVF in most countries falls short of the minimum 1500 cycles per annum that would be needed per million population. Comparative international data indicate that infertile couples would increase their uptake of IVF services if the price were lower.
体外受精（IVF）是治疗长期不孕症的一种有效但未得到充分利用的方法。根据此前公布的估计，2001年美国每个体外受精周期的预计成本中位数为9226美元，其他25个国家为3531美元。根据此前公布的估计，2001年美国因体外受精周期导致的每次分娩成本平均为56419美元，其他八个国家为20522美元。在三项随机对照试验中，体外受精的成本效益尚未得到证实，但这些试验难以设计和实施。多胎妊娠显著增加了体外受精治疗的成本。体外受精多胎分娩的成本比导致多胎分娩的体外受精周期高出36%。在大多数国家，体外受精的应用率低于每百万人口每年所需的最低1500个周期。国际比较数据表明，如果价格降低，不孕夫妇会增加对体外受精服务的使用。
