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一项基于记录的对803名在精神科接受抑郁症治疗患者的分析。

A record-based analysis of 803 patients treated for depression in psychiatric care.

作者信息

Rytsälä H J, Melartin T K, Leskelä U S, Lestelä-Mielonen P S, Sokero T P, Isometsä E T

机构信息

Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland.

出版信息

J Clin Psychiatry. 2001 Sep;62(9):701-6. doi: 10.4088/jcp.v62n0907.

Abstract

BACKGROUND

New antidepressants emerged and became widely used during the 1990s. The present study investigated quality-of-care problems in the treatment of depression in a current psychiatric setting.

METHOD

We investigated the treatment received for depression by all 803 inpatients or outpatients with a clinical diagnosis of ICD-10 depressive episode or recurrent depressive disorder in 1996 in the Peijas Medical Care District, which provides psychiatric services for citizens of Vantaa, a city in southern Finland.

RESULTS

Most patients (84%) in the sample were found to have received antidepressants, generally in adequate, albeit low, doses. Inadequate antidepressant treatment was common only with tricyclic antidepressants. Most patients received a single antidepressant for extended periods; only 22% had 2 or more antidepressant trials. During the treatment period, disability pension was granted to 19% of those not already pensioned, two thirds (67%) of whom had received only 1 antidepressant trial prior to being granted a pension.

CONCLUSION

The present study supports the emerging perception of improved quality of pharmacotherapy in psychiatric settings, with the exception of treatment with tricyclic antidepressants. Problems of quality of care now appear to be related to the suboptimal intensity and monitoring of the treatment provided. which may eventually result in considerable costs to society due to permanent disability.

摘要

背景

新型抗抑郁药于20世纪90年代出现并广泛应用。本研究调查了当前精神科环境中抑郁症治疗的护理质量问题。

方法

我们调查了1996年芬兰南部万塔市佩亚斯医疗区所有803例临床诊断为ICD - 10抑郁发作或复发性抑郁障碍的住院或门诊患者所接受的抑郁症治疗情况。该医疗区为万塔市居民提供精神科服务。

结果

样本中的大多数患者(84%)接受了抗抑郁药治疗,剂量通常足够,尽管较低。抗抑郁药治疗不足仅在三环类抗抑郁药治疗中常见。大多数患者长期服用单一抗抑郁药;只有22%的患者进行过2次或更多次抗抑郁药试验。在治疗期间,19%尚未领取残疾抚恤金的患者获得了残疾抚恤金,其中三分之二(67%)在获得抚恤金之前仅进行过1次抗抑郁药试验。

结论

本研究支持了在精神科环境中药物治疗质量有所改善的新观点,但三环类抗抑郁药治疗除外。现在护理质量问题似乎与所提供治疗的强度不足和监测不够有关,这最终可能因永久性残疾给社会带来相当大的成本。

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