Padovan Catherine, Versace Rémy, Thomas-Antérion Catherine, Laurent Bernard
Laboratoire d'Etude des Mécanismes Cognitifs, Institut de Psychologie, Université Lyon 2, 5 avenue Pierre Mendès-France, 69676, Bron, France.
Neuropsychologia. 2002;40(3):335-9. doi: 10.1016/s0028-3932(01)00101-4.
Using an affective priming paradigm, we studied the automatic and unconscious activation of emotional information in long-term memory. Participants had to judge target words preceded by various primes as positive or negative. The primes were masked and the SOA between the onset of primes and the onset of targets was 50 ms. Our results showed that in patients with dementia of the Alzheimer type (DAT), the negativity bias was preserved and the emotional priming effect was perturbed with positive targets. In control participants, this priming effect was restricted to negative targets. These findings are discussed in terms of preserved automatic activation of emotional information in Alzheimer's disease (AD) and in terms of an early deficit of the left hemisphere in AD making positive information more vulnerable to disease.
我们采用情感启动范式，研究了长期记忆中情绪信息的自动和无意识激活。参与者必须判断在各种启动刺激之后呈现的目标词是积极的还是消极的。启动刺激被掩蔽，启动刺激开始与目标刺激开始之间的刺激间隔为50毫秒。我们的结果表明，在阿尔茨海默病型痴呆（DAT）患者中，消极偏向得以保留，且积极目标的情绪启动效应受到干扰。在对照参与者中，这种启动效应仅限于消极目标。我们从阿尔茨海默病（AD）中情绪信息的自动激活得以保留，以及AD患者左半球早期缺陷使积极信息更易受疾病影响这两个方面对这些发现进行了讨论。
