Seidenberg Michael, Griffith Randall, Sabsevitz David, Moran Maria, Haltiner Alan, Bell Brian, Swanson Sara, Hammeke Thomas, Hermann Bruce
Department of Psychology, Finch University of Health Sciences/The Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064, USA.
Neuropsychologia. 2002;40(4):446-56. doi: 10.1016/s0028-3932(01)00096-3.
We examined the performance of 21 patients with unilateral temporal lobe epilepsy (TLE) and hippocampal damage (10 lefts, and 11 rights) and 10 age-matched controls on the recognition and identification (name and occupation) of well-known faces. Famous face stimuli were selected from four time periods; 1970s, 1980s, 1990-1994, and 1995-1996. Differential patterns of performance were observed for the left and right TLE group across distinct face processing components. The left TLE group showed a selective impairment in naming famous faces while they performed similar to the controls in face recognition and semantic identification (i.e. occupation). In contrast, the right TLE group was impaired across all components of face memory; face recognition, semantic identification, and face naming. Face naming impairment in the left TLE group was characterized by a temporal gradient with better naming performance for famous faces from more distant time periods. Findings are discussed in terms of the role of the temporal lobe system for the acquisition, retention, and retrieval of face semantic networks, and the differential effects of lateralized temporal lobe lesions in this process.
我们研究了21例单侧颞叶癫痫（TLE）伴海马损伤患者（10例左侧，11例右侧）以及10例年龄匹配的对照者对知名面孔的识别与辨认（姓名和职业）能力。著名面孔刺激选自四个时间段：20世纪70年代、80年代、1990 - 1994年以及1995 - 1996年。在不同的面孔加工成分上，观察到左侧和右侧TLE组的表现存在差异模式。左侧TLE组在命名著名面孔时表现出选择性损伤，而在面孔识别和语义辨认（即职业）方面，其表现与对照组相似。相比之下，右侧TLE组在面孔记忆的所有成分上均受损；包括面孔识别、语义辨认和面孔命名。左侧TLE组的面孔命名损伤具有时间梯度特征，对于来自更久远时间段的著名面孔，命名表现更好。我们从颞叶系统在面孔语义网络的获取、保留和检索中的作用，以及在此过程中颞叶侧化损伤的不同影响方面对研究结果进行了讨论。
