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股下静脉旁路移植术结局的批判性评估

Critical assessment of the outcome of infrainguinal vein bypass.

作者信息

Golledge J, Iannos J, Walsh J A, Burnett J R, Foreman R K

机构信息

Department of Vascular Surgery, The Repatriation General Hospital, Daw Park, Adelaide, South Australia.

出版信息

Ann Surg. 2001 Nov;234(5):697-701. doi: 10.1097/00000658-200111000-00017.

Abstract

OBJECTIVE

To perform a more critical assessment of infrainguinal vein bypass.

SUMMARY BACKGROUND DATA

Graft patency may give an unrealistic impression of the outcome of bypass surgery.

METHODS

During a 6-year period, 236 patients undergoing primary vein grafts were entered into the study. An ideal outcome required the patient to have survived 12 months with a patent graft on duplex scanning, no perioperative complication, and no further related open or endovascular surgery or admission.

RESULTS

At 12 months, the secondary graft patency rate was 82%; however, only 22% of patients had an ideal outcome. At 1 year, 44 (19%) patients died, 93 (39%) required further ipsilateral and 39 (17%) contralateral intervention, and a total of 108 (46%) were readmitted. An ideal outcome was more likely in patients receiving calcium channel blockers, principally because of improved primary patency, and less likely in those with cardiac failure requiring furosemide, principally because of worse survival in these patients.

CONCLUSIONS

Few patients achieve an ideal result after infrainguinal vein bypass. Outcome may be improved by the use of calcium channel blockers. Careful consideration is required before performing revascularization in patients with cardiac failure.

摘要

目的

对股下静脉搭桥术进行更严格的评估。

总结背景资料

移植血管通畅可能会给搭桥手术的结果带来不切实际的印象。

方法

在6年期间,236例行原发性静脉移植的患者纳入本研究。理想的结果要求患者在双功扫描时移植血管通畅存活12个月,无围手术期并发症,且无进一步的相关开放手术、血管腔内手术或住院治疗。

结果

12个月时,移植血管的二级通畅率为82%;然而,只有22%的患者获得了理想的结果。1年时,44例(19%)患者死亡,93例(39%)需要进一步进行同侧干预,39例(17%)需要对侧干预,共有108例(46%)患者再次入院。接受钙通道阻滞剂治疗的患者更有可能获得理想的结果,主要是因为原发性通畅率提高;而需要使用速尿治疗的心力衰竭患者获得理想结果的可能性较小,主要是因为这些患者的生存率较低。

结论

股下静脉搭桥术后很少有患者能达到理想的结果。使用钙通道阻滞剂可能会改善结果。对心力衰竭患者进行血管重建术前需要仔细考虑。

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