Narozny W, Stankiewicz C, Przewoźny T, Bakowska A, Czuszyńska Z
ENT Department, Medical University of Gdańsk, Poland.
Acta Otorhinolaryngol Belg. 2001;55(3):227-33.
A case of multisymptomatic relapsing polychondritis in a 22-year-old woman. We report a case of a 22-year-old woman with relapsing polychondritis (RP)--a rare and little known systemic autoimmune disease characterised by episodic inflammation of cartilaginous structures (ear, nose, bronchi, trachea, larynx, ribs, cardiovascular system). This patient presents with a seven-year history, initiated by the saddle nose. The patient developed a multitude of symptoms: auricular chondritis, ocular symptoms, recurrent arthritis, respiratory complications (laryngotracheomalacia, bilateral vocal cord palsy), sensorineural hearing loss and enchondroma of the humeral bone. The examination of an auricle biopsy by an immunofluorescent method and a positive serum reaction from the patient to normal cartilage supported the immunological nature of relapsing polychondritis. Treatment consisted of orally administered prednisone and diaminodiphenylsulfone (Dapsone).
一名22岁女性的多症状复发性多软骨炎病例。我们报告了一例22岁患有复发性多软骨炎（RP）的女性病例，RP是一种罕见且鲜为人知的全身性自身免疫性疾病，其特征为软骨结构（耳、鼻、支气管、气管、喉、肋骨、心血管系统）的发作性炎症。该患者有七年病史，始于鞍鼻。患者出现了多种症状：耳廓软骨炎、眼部症状、复发性关节炎、呼吸并发症（喉气管软化、双侧声带麻痹）、感音神经性听力损失和肱骨内生软骨瘤。通过免疫荧光法对耳廓活检进行检查以及患者血清对正常软骨呈阳性反应，支持了复发性多软骨炎的免疫学性质。治疗包括口服泼尼松和氨苯砜。
