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Effective prophylaxis with daily recombinant factor VIIa (rFVIIa-Novoseven) in a child with high titre inhibitors and a target joint.

作者信息

Saxon B R, Shanks D, Jory C B, Williams V

出版信息

Thromb Haemost. 2001 Oct;86(4):1126-7.

PMID:11686341
Abstract
摘要

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1
Effective prophylaxis with daily recombinant factor VIIa (rFVIIa-Novoseven) in a child with high titre inhibitors and a target joint.
Thromb Haemost. 2001 Oct;86(4):1126-7.
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Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors.使用重组凝血因子VIIa（诺其）对有抑制物的血友病患者轻至中度出血发作进行家庭治疗。
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Relationship between factor VII activity and clinical efficacy of recombinant factor VIIa given by continuous infusion to patients with factor VIII inhibitors.持续输注重组凝血因子VIIa治疗VIII因子抑制物患者时，凝血因子VII活性与临床疗效的关系
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Prospective, randomised trial of two doses of rFVIIa (NovoSeven) in haemophilia patients with inhibitors undergoing surgery.两剂重组活化凝血因子VII（诺其）用于有抑制物的血友病患者手术的前瞻性随机试验
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Recombinant factor VIIa for patients with inhibitors to factor VIII or IX or factor VII deficiency.重组凝血因子VIIa用于治疗VIII因子、IX因子抑制剂或VII因子缺乏的患者。
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Prophylaxis in 10 patients with severe haemophilia A and inhibitor: different approaches for different clinical situations.10例重度甲型血友病伴抑制物患者的预防治疗：针对不同临床情况的不同方法。
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Home treatment of haemarthroses using a single dose regimen of recombinant activated factor VII in patients with haemophilia and inhibitors. A multi-centre, randomised, double-blind, cross-over trial.血友病及存在抑制剂患者使用单剂量重组活化因子VII进行关节积血的家庭治疗。一项多中心、随机、双盲、交叉试验。
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Increased Accumulation and Retention of rhFVIIa (eptacog beta) in Knee Joints of Hemophilia A Mice Compared to Wild-Type Mice.与野生型小鼠相比，血友病 A 小鼠膝关节中 rhFVIIa（eptacog beta）的蓄积和滞留增加。
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The expanding role of prophylaxis with recombinant activated factor VII.
重组活化凝血因子 VII 在预防治疗中的作用不断扩大。
Blood Transfus. 2013 Jan;11(1):12-3. doi: 10.2450/2012.0061-12. Epub 2012 Jul 4.
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Critical appraisal of the role of recombinant activated factor VII in the treatment of hemophilia patients with inhibitors.重组活化凝血因子VII在治疗伴有凝血因子抑制物的血友病患者中作用的批判性评价
J Blood Med. 2010;1:37-48. doi: 10.2147/JBM.S6209. Epub 2010 Mar 30.
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Recurrent miscarriage and antiphospholipid antibodies: prognosis of subsequent pregnancy.复发性流产与抗磷脂抗体：对后续妊娠的预后影响。
J Thromb Haemost. 2010 Oct;8(10):2208-13. doi: 10.1111/j.1538-7836.2010.04015.x.
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rFVIIa transported from the blood stream into tissues is functionally active.从血流转运至组织中的重组活化凝血因子VII（rFVIIa）具有功能活性。
J Thromb Haemost. 2010 Oct;8(10):2318-21. doi: 10.1111/j.1538-7836.2010.04010.x.
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Animal models of FVIIa gene expression: their role in the future development of haemophilia treatment.动物模型中的 FVIIa 基因表达：在未来血友病治疗中的作用。
Haemophilia. 2010 Mar;16 Suppl 2(0 2):24-7. doi: 10.1111/j.1365-2516.2009.02199.x.
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Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa).药物管理的重组因子 VIIa（rFVIIa）的生物分布。
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Factor eight inhibitor bypass activity (FEIBA) in the management of bleeds in hemophilia patients with high-titer inhibitors.八因子抑制剂旁路活性（FEIBA）在高滴度抑制剂血友病患者出血管理中的应用
Vasc Health Risk Manag. 2007;3(4):527-31.
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Postoperative pulmonary thromboembolism possibly associated with recombinant activated factor VII infusion for the treatment of uncontrolled hemorrhage during vertebral instrumentation.术后肺血栓栓塞可能与重组活化凝血因子VII输注治疗椎体器械固定术中难以控制的出血有关。
J Anesth. 2007;21(2):258-60. doi: 10.1007/s00540-006-0481-y. Epub 2007 May 30.