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非体外循环下诺伍德手术的经验。

Experience with the Norwood procedure without circulatory arrest.

作者信息

Imoto Y, Kado H, Shiokawa Y, Minami K, Yasui H

机构信息

Cardiovascular Surgery, Fukuoka Children's Hospital, Kyusyu University, Fukuoka, Japan.

出版信息

J Thorac Cardiovasc Surg. 2001 Nov;122(5):879-82. doi: 10.1067/mtc.2001.116948.

Abstract

OBJECTIVE

We evaluated a new cardiopulmonary bypass technique that allowed complete avoidance of circulatory arrest and deep hypothermia in the Norwood procedure for hypoplastic left heart syndrome.

METHODS

A total of 10 patients were included in this study. The arterial line of the cardiopulmonary bypass circuit was divided in two in a Y shape; one branch was used for cerebral perfusion through the innominate artery and the other for lower body perfusion through the cannula inserted into the descending thoracic aorta. Moderate hypothermia (29 degrees C-31 degrees C rectal temperature) and high pump flow (150-180 mL. kg(-1). min(-1)) were used. A valveless conduit between the right ventricle and the pulmonary artery was used in 6 patients as an alternative pulmonary blood source to a conventional Blalock-Taussig shunt (n = 4).

RESULTS

Circulatory arrest was completely avoided throughout the operation in all cases, and no complications from the new cardiopulmonary bypass technique were seen. Early deaths occurred in 3 cases. Neurologic deficits were not seen among the survivors, and the postoperative course was stable and uneventful, including satisfactory renal function.

CONCLUSIONS

The Norwood procedure for hypoplastic left heart syndrome was successfully accomplished with complete avoidance of circulatory arrest by means of cerebral perfusion through the innominate artery combined with cannulation of the descending aorta. A conduit between the right ventricle and the pulmonary artery seems an excellent alternative pulmonary blood source, although right ventricular function needs to be carefully monitored.

摘要

目的

我们评估了一种新的体外循环技术,该技术可在左心发育不全综合征的诺伍德手术中完全避免循环骤停和深度低温。

方法

本研究共纳入10例患者。体外循环回路的动脉管道呈Y形分为两支;一支通过无名动脉用于脑灌注,另一支通过插入降主动脉的插管用于下半身灌注。采用中度低温(直肠温度29摄氏度至31摄氏度)和高泵流量(150 - 180 mL·kg⁻¹·min⁻¹)。6例患者使用右心室与肺动脉之间的无瓣管道作为传统布莱洛克 - 陶西格分流术(n = 4)的替代肺血源。

结果

所有病例在整个手术过程中均完全避免了循环骤停,且未发现新的体外循环技术相关并发症。3例发生早期死亡。幸存者中未出现神经功能缺损,术后病程稳定且顺利,包括肾功能良好。

结论

通过无名动脉脑灌注联合降主动脉插管,成功完成了左心发育不全综合征的诺伍德手术,完全避免了循环骤停。右心室与肺动脉之间的管道似乎是一种极好的替代肺血源,尽管需要仔细监测右心室功能。

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