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采用自体心包补片对新生儿进行主动脉弓重建:当代结果

Aortic arch reconstruction in newborns with an autologous pericardial patch: contemporary results.

作者信息

Bernabei Massimo, Margaryan Rafik, Arcieri Luigi, Bianchi Giacomo, Pak Vitali, Murzi Bruno

机构信息

Department of Congenital Heart Disease, Ospedale Del Cuore Fondazione G. Monasterio, Massa, Italy.

出版信息

Interact Cardiovasc Thorac Surg. 2013 Mar;16(3):282-5. doi: 10.1093/icvts/ivs510. Epub 2012 Dec 7.

Abstract

OBJECTIVES

The incidence of recurrent aortic arch obstruction after Norwood procedure and other types of aortic arch reconstruction in newborns remains high. Biological and synthetic materials are used to enlarge the aorta. We report our experience using autologous pericardium to reconstruct the aortic arch in patients with hypoplastic left heart syndrome, aortic arch interruption and hypoplastic aortic arch.

METHODS

A retrospective analysis of 39 consecutively operated patients evaluated after an initial Norwood and other types aortic arch repair was performed. The presence of recurrent arch obstruction (mean gradient ≥ 20 mmHg) and its management were noted. The mean weight of our patients was 3.2 ± 0.7 kg.

RESULTS

The mean age at primary surgical correction was 7.4 ± 6.8 (range 1-35 days). All patients were discharged without a significant residual gradient at the aortic arch except 4 who had a peak gradient of ≥ 30 mmHg. The overall incidence of recurrent arch obstruction was 28.2% (11 patients). Four (12.1%) patients had a distal obstruction, 1 (3%) had proximal obstruction and 1 had a mid-transverse arch obstruction. All patients underwent aortic arch reintervention consisting of balloon dilatation, and only after unsuccessful dilatation, 3 underwent surgical patch aortoplasties.

CONCLUSIONS

The use of autologous pericardium in aortic arch reconstruction procedure is effective and associated with an acceptable incidence of recurrent arch obstruction. Its availability and characteristics make it an attractive alternative to other materials.

摘要

目的

在新生儿中,诺伍德手术及其他类型的主动脉弓重建术后,主动脉弓梗阻复发的发生率仍然很高。生物材料和合成材料被用于扩大主动脉。我们报告了使用自体心包重建左心发育不全综合征、主动脉弓中断及主动脉弓发育不全患者的主动脉弓的经验。

方法

对39例接受初次诺伍德手术及其他类型主动脉弓修复术后接受评估的连续手术患者进行回顾性分析。记录复发性弓部梗阻(平均压差≥20 mmHg)的存在情况及其处理方式。我们患者的平均体重为3.2±0.7 kg。

结果

初次手术矫正时的平均年龄为7.4±6.8(范围1 - 35天)。除4例峰值压差≥30 mmHg的患者外,所有患者出院时主动脉弓均无明显残余压差。复发性弓部梗阻的总体发生率为28.2%(11例患者)。4例(12.1%)患者有远端梗阻,1例(3%)有近端梗阻,1例有横断主动脉弓中段梗阻。所有患者均接受了包括球囊扩张在内的主动脉弓再次干预,只有在扩张失败后,3例患者接受了手术补片主动脉成形术。

结论

在主动脉弓重建手术中使用自体心包是有效的,且复发性弓部梗阻的发生率可接受。其可用性和特性使其成为其他材料的有吸引力的替代物。

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