从纳塔尔真核木中分离得到的柿素对结核分枝杆菌药敏株和耐药株的抑制作用
Inhibition of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis by diospyrin, isolated from Euclea natalensis.
作者信息
Lall N, Meyer J J
机构信息
Department of Botany, University of Pretoria, Pretoria 0002, South Africa.
出版信息
J Ethnopharmacol. 2001 Dec;78(2-3):213-6. doi: 10.1016/s0378-8741(01)00356-7.
Abstract
The binaphthoquinoid, diospyrin, was isolated from Euclea natalensis A.DC., and evaluated for its activity against drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis. The minimal inhibitory concentration (MIC) of diospyrin was found to be 100 microg/ml for all the M. tuberculosis strains.
摘要
从纳塔尔柿（Euclea natalensis A.DC.）中分离出双萘醌类化合物——柿素，并对其针对结核分枝杆菌敏感株和耐药株的活性进行了评估。结果发现，柿素对所有结核分枝杆菌菌株的最低抑菌浓度（MIC）均为100微克/毫升。
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