Cappellano F, Bertapelle P, Spinelli M, Catanzaro F, Carone R, Zanollo A, De Seta F, Giardiello G
Policlinico Multimedica, Sesto S. Giovanni, Ospedale Fornaroli, Magenta, CTO/CRF/MA, Torino and Medtronic Italy, Milano, Italy.
J Urol. 2001 Dec;166(6):2277-80.
We investigated the impact of sacral neuromodulation on quality of life and assessed the importance of quality of life for determining the success of sacral neuromodulation in patients with detrusor hyperactivity, including instability and hyperreflexia. We also compared it with parameters documented in a voiding diary.
From May 1998 to December 2000, 82 female and 31 male patients 17 to 79 years old (mean age 51.1) with urge incontinence (63), urgency/frequency (5), voiding disturbance (41) and pelvic pain (4) resistant to conservative treatment were enrolled in a national prospective registry after showing a positive response to percutaneous nerve evaluation testing. Of the patients 47 who were 32 to 79 years old (mean age 59.2) with urge incontinence due to detrusor instability and 16 who were 27 to 51 years old (mean age 51.5) with hyperreflexia were asked to complete a validated self-reporting incontinence domain specific quality of life questionnaire before, and 3, 6, 9, 12, 18, 24 and 36 months after implantation.
Compared with baseline the quality of life index significantly improved at each followup, which strongly correlated with the decrease in the number of incontinence episodes.
Evaluating quality of life may be an additional useful tool for assessing the results of sacral neuromodulation for urge incontinence. Our study confirms that sacral neuromodulation is effective therapy for urge incontinence that can have a positive effect on patient quality of life.
我们研究了骶神经调节对生活质量的影响,并评估了生活质量对于确定逼尿肌过度活动(包括不稳定和反射亢进)患者骶神经调节成功与否的重要性。我们还将其与排尿日记中记录的参数进行了比较。
从1998年5月至2000年12月,82名女性和31名男性患者,年龄在17至79岁(平均年龄51.1岁),患有急迫性尿失禁(63例)、尿急/尿频(5例)、排尿障碍(41例)和盆腔疼痛(4例),经保守治疗无效,在经皮神经评估测试显示阳性反应后,纳入一项全国性前瞻性登记研究。其中47例年龄在32至79岁(平均年龄59.2岁),因逼尿肌不稳定导致急迫性尿失禁,16例年龄在27至51岁(平均年龄51.5岁),患有反射亢进,要求他们在植入前以及植入后3、6、9、12、18、24和36个月完成一份经过验证的特定于尿失禁领域的自我报告生活质量问卷。
与基线相比,每次随访时生活质量指数均显著改善,这与尿失禁发作次数的减少密切相关。
评估生活质量可能是评估骶神经调节治疗急迫性尿失禁效果的另一个有用工具。我们的研究证实,骶神经调节是治疗急迫性尿失禁的有效疗法,可对患者生活质量产生积极影响。