Escutenaire S, Pastoret P P
Faculté de Médecine vétérinaire, Université de Liège au Sart-Tilman.
Bull Mem Acad R Med Belg. 2001;156(1-2):137-44; discussion 144-6.
In Europe, Puumala (PUU) is a hantavirus responsible for a human disease called nephropathia epidemica and its natural reservoir is the red bank vole, (Clethrionomys glareolus). Although the population densities and the prevalence rates of infection were high in red bank voles in southern Belgium during the 1996 and 1999 epidemic years, the percentages of infected rodents were low in 1997 and 1998, when only a few positive sites were found. Antibodies against PUU virus were mainly detected in the red bank vole but also in the wood mouse (Apodemus sylvaticus) and the red fox (Vulpes vulpes). The analysis of genomic sequences has shown that the Belgian viruses and the German strain Erft constitute a genetic lineage well separated from the other European PUU strains.
在欧洲,普马拉病毒(PUU)是一种引发人类流行性肾病的汉坦病毒,其天然宿主是赤背 vole(棕背䶄)。尽管在1996年和1999年疫情期间,比利时南部赤背 vole 的种群密度和感染率很高,但在1997年和1998年,感染啮齿动物的比例较低,当时仅发现了少数阳性位点。针对普马拉病毒的抗体主要在赤背 vole 中检测到,但也在林姬鼠(小家鼠)和赤狐中检测到。基因组序列分析表明,比利时病毒和德国埃尔夫特毒株构成了一个与其他欧洲普马拉病毒株明显不同的遗传谱系。