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[1,3;1,6-β-D-葡聚糖转位酶:研究结果与应用前景]

[1,3;1,6-beta-D-glucan translam: results of studying and prospects for application].

作者信息

Ivanushko L A, Besednova N N, Zaporozhets T S, Zviagintseva T N

机构信息

Research Institute of Epidemiology and Microbiology, Siberian Branch of the Russian Academy of Medical Sciences, Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Vladivostok.

出版信息

Antibiot Khimioter. 2001;46(7):14-8.

Abstract

The results of translam chemical structure and biological activity investigation are presented. Translam is a new original semisynthetic polysaccharide of marine origin. The preparation demonstrated potent treatment effect in experimental radiation disease. It had preventing effect at experimental bacterial infections, stimulated hematopoiesis, had effect on humoral and cell immunity and on factors of nonspecific organism resistance.

摘要

本文展示了对Translam化学结构和生物活性的研究结果。Translam是一种新型的源自海洋的原创半合成多糖。该制剂在实验性辐射病中显示出显著的治疗效果。它对实验性细菌感染有预防作用,能刺激造血,对体液免疫和细胞免疫以及机体非特异性抵抗力的因素有影响。

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