[从海洋微生物溶藻弧菌获得的胞外多糖的免疫调节特性]
[Immunotropic properties of exoglycan obtained from the marine micro-organism Vibrio alginolyticus].
作者信息
Smolina T P, Gorshkova R P, Nazarenko E L, Ivanushko L A, Zaporozhets T S, Besednova N N
机构信息
Research Institute of Epidemiology and Microbiology, Siberian Branch, Russian Academy of Medical Sciences, Vladivostok.
出版信息
Antibiot Khimioter. 2002;47(1):7-11.
PMID:12077940
Abstract
Immune system modulating activity of exoglycane isolated from culture media of Vibrio alginolyticus (strain 945-80) was investigated. The substance demonstrated stimulating activity on the humoral and cell immune system, potentiated phagocyte activity of macrophage and neutrophils, increased survival index of the animals infected by Gram-positive and Gram-negative bacteria.
摘要
研究了从溶藻弧菌（菌株945 - 80）培养基中分离出的外聚糖的免疫系统调节活性。该物质对体液和细胞免疫系统表现出刺激活性，增强了巨噬细胞和中性粒细胞的吞噬活性，提高了感染革兰氏阳性菌和革兰氏阴性菌的动物的存活指数。
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