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聚(U,s4-U)作为一种合成信使核糖核酸,用于在源自大鼠肝脏的无细胞系统中合成聚苯丙氨酸。

Poly (U, s 4-U) as a synthetic messenger RNA for polyphenylalanine synthesis in a cell-free system derivem derived from rat liver.

作者信息

Keren-Zur M, Hochberg A A, Groot N D, Lapidot Y

出版信息

Nucleic Acids Res. 1975 Apr;2(4):595-601. doi: 10.1093/nar/2.4.595.

Abstract

Two different U and S4-U containing polymers with U:s4U ratio of 3:1 and 5:1 were synthesized. Their activity as messenger RNA was studied in an amino acid incorporation cell-free system from rat liver. It was shown that both copolymers can stimulate the incorporation of phenylalanine into oligophynylalamyl-tRNA.

摘要

合成了两种不同的含尿苷(U)和4-硫尿苷(S4-U)的聚合物,其U:S4-U比例分别为3:1和5:1。在大鼠肝脏的无细胞氨基酸掺入系统中研究了它们作为信使核糖核酸的活性。结果表明,两种共聚物均可刺激苯丙氨酸掺入寡聚苯丙氨酰-tRNA中。

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