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活体供者的经历:活体肝移植后的供者健康评估及结果

The living donor experience: donor health assessment and outcomes after living donor liver transplantation.

作者信息

Beavers K L, Sandler R S, Fair J H, Johnson M W, Shrestha R

机构信息

Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7080, USA.

出版信息

Liver Transpl. 2001 Nov;7(11):943-7. doi: 10.1053/jlts.2001.28443.

Abstract

Despite the increasing use of living donor liver transplantation, little is known about donor needs, concerns, and experiences. The goal of this study is to assess morbidity associated with living donation from a donor perspective, functional status after donation, and overall satisfaction with the donation process. We surveyed all living donors (LDs) from our center. Demographics, perioperative experience, and satisfaction with donation were assessed. The Medical Outcomes Study 12-Item Short-Form Survey (SF-12), a well-validated tool, measured overall health-related quality of life. Of 27 subjects eligible for the study, 27 subjects (100%) participated. Forty percent reported an event they deemed an immediate complication, of which 60% were recorded in the medical record. Complications requiring readmission were reported by 22%. Mean recovery time was 12 weeks (range, 1 to 52 weeks). No significant change was reported in physical activity, social activity, or emotional stability, and 92% of donors resumed their predonation occupation. Regardless of recipient outcome, 100% of donors would donate again and recommend donation to someone in contemplation. All surveyed LDs at our institution are satisfied with their donation decision. Morbidity in the first year after donation may be greater than previously appreciated. Despite complications, postoperative functional status of donors is equal to or better than population norms.

摘要

尽管活体供肝移植的应用越来越多,但对于供体的需求、担忧和经历却知之甚少。本研究的目的是从供体角度评估活体捐赠相关的发病率、捐赠后的功能状态以及对捐赠过程的总体满意度。我们对本中心的所有活体供体进行了调查。评估了人口统计学特征、围手术期经历以及对捐赠的满意度。使用经过充分验证的医学结局研究简明健康调查量表(SF-12)来衡量总体健康相关生活质量。在27名符合研究条件的受试者中,27名受试者(100%)参与了研究。40%的受试者报告了他们认为是即刻并发症的事件,其中60%记录在病历中。22%的受试者报告了需要再次入院治疗的并发症。平均恢复时间为12周(范围为1至52周)。身体活动、社交活动或情绪稳定性方面未报告有显著变化,92%的供体恢复了捐赠前的工作。无论受者的结局如何,100%的供体愿意再次捐赠并向考虑捐赠的人推荐。我们机构所有接受调查的活体供体对他们的捐赠决定都很满意。捐赠后第一年的发病率可能比之前认为的更高。尽管有并发症,但供体术后的功能状态等于或优于人群标准。

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