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右肝叶捐献:对供体生活质量的影响

Right hepatic lobe donation: impact on donor quality of life.

作者信息

Sevmis S, Diken T, Boyvat F, Torgay A, Haberal M

机构信息

Department of General Surgery, Başkent University Faculty of Medicine, Ankara, Turkey.

出版信息

Transplant Proc. 2007 May;39(4):826-8. doi: 10.1016/j.transproceed.2007.02.045.

Abstract

The aim of this study was to assess the impact of living-donor liver transplantation on the donor's quality of life. Among the 48 performed at our hospital from October 2003 to June 2006, 46 (27 men, 19 women; mean age, 37.4 years) were followed for more than 4 months (mean, 16.5+/-8 months). In April 2006, these donors participated in a survey that included medical and psychosocial outcomes. Seven complications occurred in four of 46 donors (8.6%): two biliary leaks, two wound infections, one incisional hernia, one portal vein thrombosis, and one deep venous thrombosis. For the donor with portal vein thrombosis, the vein was recanalized, and she recovered without treatment; a bile leak from the cut liver surface and an incisional hernia also developed in the same donor. The biliary leak was treated with percutaneous drainage, and the incisional hernia was repaired surgically. Fifteen donors were housewives, 31 worked outside the home, and 94% returned to their work. A change in body image was reported in 4.3% of the donors. None reported impaired sexual function. Complete recovery occurred in 86% of donors, 94% of the donors said that they would donate again if necessary, and 97% believe that they had benefited from the donation experience. In conclusion, almost all donors were able to return to their prior jobs within a few months of surgery, and most donors were satisfied with the donation procedure.

摘要

本研究的目的是评估活体肝移植对供者生活质量的影响。在2003年10月至2006年6月间于我院进行的48例活体肝移植中,46例(27名男性,19名女性;平均年龄37.4岁)接受了超过4个月(平均16.5±8个月)的随访。2006年4月,这些供者参与了一项涵盖医学和社会心理结果的调查。46例供者中有4例(8.6%)出现了7种并发症:2例胆漏、2例伤口感染、1例切口疝、1例门静脉血栓形成和1例深静脉血栓形成。对于发生门静脉血栓形成的供者,静脉再通,未经治疗即康复;同一供者还出现了切肝表面胆漏和切口疝。胆漏采用经皮引流治疗,切口疝通过手术修复。15名供者为家庭主妇,31名在外工作,94%的供者恢复了工作。4.3%的供者报告身体形象有变化。无人报告性功能受损。86%的供者完全康复,94%的供者表示如有必要愿意再次捐献,97%的供者认为他们从捐献经历中受益。总之,几乎所有供者在术后几个月内都能够恢复到之前的工作,并且大多数供者对捐献过程感到满意。

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