Calongne K B, Aichelmann-Reidy M E, Yukna R A, Mayer E T
Periodontics Department, Baltimore College of Dental Surgery, University of Maryland, Baltimore, MD, USA.
J Periodontol. 2001 Oct;72(10):1451-9. doi: 10.1902/jop.2001.72.10.1451.
Class II furcations present difficult treatment problems. Several treatment approaches to obtain furcation fill have been used with varying success.
The response of mandibular Class II furcations to treatment with either a microporous biocompatible composite of PMMA (poly-methyl-methacrylate), PHEMA (poly-hydroxyl-ethyl methacrylate) and calcium hydroxide graft synthetic bone (HTR) replacement graft material; ePTFE barrier membrane; or a combination of the two was evaluated in trios of mandibular molars with Class II furcations in 8 patients with moderate to advanced periodontitis. Following initial preparation, full-thickness flaps were raised in the areas being treated, the bone and furcation defects debrided of granulomatous tissue, and the involved root surfaces mechanically prepared and chemically conditioned. By random allocation, HTR, ePTFE, or a combination of both was placed into and/or fitted over the furcations, packed and/or secured in place, and the host flap replaced or coronally positioned with sutures. Postsurgical deplaquing was performed every 10 days leading up to ePTFE removal at approximately 6 weeks. Continuing periodontal maintenance therapy was provided until surgical reentry at 6 months for documentation and any further necessary treatment.
Direct clinical measurements demonstrated essentially similar clinical results with all 3 treatments for bone and soft tissue changes. There were no statistically or clinically significant differences except for better horizontal amount and percent defect fill with HTR alone. Four of 8 furcations became Class I clinically with HTR alone, 5 of 8 became Class I with ePTFE alone, and 5 of 8 with combination treatment. The only complete furcation closure occurred with HTR.
The findings of this study suggest essentially equal clinical results with HTR bone replacement graft material alone, ePTFE barrier alone, and a combination of the two in mandibular molar Class II furcations. However, a real difference may not have been detected based on the small number of subjects in the study.
Ⅱ度根分叉病变存在治疗难题。已采用多种治疗方法来实现根分叉填充,但效果各异。
在8例中重度牙周炎患者的下颌磨牙Ⅱ度根分叉病变中,对采用聚甲基丙烯酸甲酯(PMMA)、聚甲基丙烯酸羟乙酯(PHEMA)和氢氧化钙接枝合成骨(HTR)的微孔生物相容性复合材料替代移植材料、ePTFE屏障膜或两者联合治疗的效果进行了评估。初始准备后,在治疗区域掀起全厚瓣,清除骨和根分叉缺损处的肉芽组织,对受累根面进行机械预备和化学处理。通过随机分配,将HTR、ePTFE或两者联合置于根分叉内和/或覆盖在根分叉上,填充和/或固定到位,然后将宿主瓣复位或冠向定位并缝合。术后每10天进行一次菌斑清除,直至约6周时去除ePTFE。持续进行牙周维护治疗,直至6个月时再次手术以记录情况并进行任何必要的进一步治疗。
直接临床测量显示,所有3种治疗方法在骨和软组织变化方面的临床结果基本相似。除单独使用HTR时水平向骨量和缺损填充百分比更好外,无统计学或临床显著差异。单独使用HTR时,8个根分叉中有4个在临床上变为Ⅰ度;单独使用ePTFE时,8个中有5个变为Ⅰ度;联合治疗时,8个中有5个变为Ⅰ度。唯一完全的根分叉闭合发生在使用HTR时。
本研究结果表明,在下颌磨牙Ⅱ度根分叉病变中,单独使用HTR骨替代移植材料、单独使用ePTFE屏障膜以及两者联合使用的临床结果基本相同。然而,基于研究中的受试者数量较少,可能未检测到真正的差异。