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使用可吸收引导组织再生膜治疗Ⅱ度根分叉病变:一项为期6个月的研究。

Treatment of grade II furcation involvement using resorbable guided tissue regeneration membrane: A six-month study.

作者信息

Khanna Deepti, Malhotra Sumit, Naidu D Venugopal

机构信息

Department of Periodontology and Oral Implantology, I.T.S. Center for Dental Studies and Research, Muradnagar, Ghaziabad, Uttar Pradesh, India.

出版信息

J Indian Soc Periodontol. 2012 Jul;16(3):404-10. doi: 10.4103/0972-124X.100920.

Abstract

AIMS

The present study was undertaken to evaluate the effectiveness of the combination of hydroxyapatite and β-tricalcium phosphate bone alloplast with bioresorbable guided tissue regeneration membrane for the treatment of mandibular grade II furcation defects.

SETTINGS AND DESIGN

A total of eight patients, four females and four males, in the age group of 18 to 65 years, with bilateral buccal grade II furcation defects in the mandibular molars, participated in the study.

MATERIALS AND METHODS

THE FOLLOWING CLINICAL MEASUREMENTS WERE RECORDED AT BASELINE AS WELL AS THREE AND SIX MONTHS POST SURGERY: The Turesky-Gilmore-Glickman modification of the Quigley Hein plaque index, the Loe and Silness gingival index, Relative Clinical Attachment Level Vertical Probing Depth in the mid-furcation area, and Horizontal Probing Depth in the mid-furcation area.

STATISTICAL ANALYSIS

Pairwise comparisons within the groups were done by applying the independent student t test. Comparisons were also drawn between the test and the control groups by applying the independent student t test.

RESULTS

The mean gain in the relative clinical attachment levels in the test and control groups, at the end of six months, were 2.50 and 1.63 mm, respectively. The mean change in the horizontal probing depth values at the end of six months in the test and control groups were 2.88 and 1.63 mm, respectively. The mean reduction in the vertical probing depth values in the test and control groups were 1.50 and 1.38 mm, respectively.

CONCLUSIONS

The resorbable GTR membrane with bone material was more effective than open debridement alone, in the treatment of furcation defects.

摘要

目的

本研究旨在评估羟基磷灰石和β-磷酸三钙异体骨与生物可吸收引导组织再生膜联合应用治疗下颌Ⅱ度根分叉病变的有效性。

设置与设计

共有8例患者参与本研究,年龄在18至65岁之间,包括4名女性和4名男性,均为下颌磨牙双侧颊侧Ⅱ度根分叉病变。

材料与方法

在基线以及术后3个月和6个月记录以下临床指标:对Quigley Hein菌斑指数进行Turesky-Gilmore-Glickman改良、Loe和Silness牙龈指数、根分叉中部区域的相对临床附着水平垂直探诊深度以及根分叉中部区域的水平探诊深度。

统计分析

组内两两比较采用独立样本t检验。试验组与对照组之间的比较也采用独立样本t检验。

结果

6个月末,试验组和对照组相对临床附着水平的平均增加量分别为2.50 mm和1.63 mm。6个月末,试验组和对照组水平探诊深度值的平均变化分别为2.88 mm和1.63 mm。试验组和对照组垂直探诊深度值的平均减少量分别为1.50 mm和1.38 mm。

结论

在治疗根分叉病变方面,带有骨材料的可吸收引导组织再生膜比单纯开放清创更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30b5/3498712/93153480e469/JISP-16-404-g001.jpg

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