Keusch F, Riehle I, Fritz-Niggli H
Experientia. 1975 Jul 15;31(7):844-6. doi: 10.1007/BF01938498.
Mutations-induction followed by selection is a suitable method for developing a cell line with resistance to low doses of X-rays. In comparison with the original cell line, the derived resistant line is characterized by an enhanced variability of the chromosome number, and no higher level of cellular repair, limited to the two repair types described.
先进行突变诱导再进行筛选是培育对低剂量X射线具有抗性的细胞系的一种合适方法。与原始细胞系相比,衍生出的抗性细胞系的特征是染色体数目的变异性增强,且细胞修复水平并未提高,仅限于所描述的两种修复类型。