O'Brien J A, Caro I, Getsios D, Caro J J
Caro Research, 336 Baker Avenue, Concord, MA 01742, USA.
Value Health. 2001 May-Jun;4(3):258-65. doi: 10.1046/j.1524-4733.2001.43017.x.
To estimate direct medical costs of managing major macrovascular complications in diabetic patients.
Costs were estimated for acute myocardial infarction (AMI) and ischemic stroke by applying unit costs to typical resource use profiles. Data were obtained from many Canadian sources, including the Ontario Case Cost Project, provincial physician and laboratory fee schedules, provincial formularies, government reports, and peer-reviewed literature. For each complication, the event costs per patient are those associated with resource use specific to the acute episode and any subsequent care occurring in the first year. State costs are the annual costs per patient of continued management. All costs are expressed in 1996 Canadian dollars.
Acute hospital care accounts for approximately half of the first year management costs ($15,125) of AMI. Given the greater need for postacute care, acute hospital care has less impact (28%) on event costs for stroke ($31,076). The state costs for AMI and stroke are $1544 and $8141 per patient, respectively.
Macrovascular complications of diabetes potentially represent a substantial burden to Canada's health care system. As new therapies emerge that may reduce the incidence of some diabetic complications, decision makers will need information to make critical decisions regarding how to spend limited health care dollars. Published literature lacks Canadian-specific cost estimates that may be readily translated into patient-level cost inputs for an economic model. This paper provides two key pieces of the many needed to understand the scope of the economic burden of diabetes and its complications for Canada.
评估糖尿病患者主要大血管并发症的直接医疗成本。
通过将单位成本应用于典型资源使用概况来估算急性心肌梗死(AMI)和缺血性中风的成本。数据来自加拿大的多个来源,包括安大略病例成本项目、省级医生和实验室收费表、省级药品目录、政府报告以及同行评审文献。对于每种并发症,每位患者的事件成本是与急性发作特定的资源使用以及第一年发生的任何后续护理相关的成本。国家成本是每位患者持续管理的年度成本。所有成本均以1996年加拿大元表示。
急性住院治疗约占AMI第一年管理成本(15,125加元)的一半。鉴于对急性后期护理的需求更大,急性住院治疗对中风事件成本(31,076加元)的影响较小(28%)。AMI和中风的国家成本分别为每位患者1544加元和8141加元。
糖尿病的大血管并发症可能给加拿大医疗保健系统带来巨大负担。随着可能降低某些糖尿病并发症发病率的新疗法出现,决策者将需要信息来做出关于如何使用有限医疗保健资金的关键决策。已发表的文献缺乏可轻松转化为经济模型中患者层面成本投入的加拿大特定成本估计。本文提供了理解糖尿病及其并发症对加拿大经济负担范围所需的众多关键信息中的两条。