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香港与糖尿病相关并发症有关的年度直接医疗费用,包括当年及随后几年的费用。

Annual direct medical costs associated with diabetes-related complications in the event year and in subsequent years in Hong Kong.

机构信息

Department of Family Medicine and Primary Care, University of Hong Kong, Ap Lei Chau, Hong Kong.

Department of Medicine, University of Hong Kong, Ap Lei Chau, Hong Kong.

出版信息

Diabet Med. 2017 Sep;34(9):1276-1283. doi: 10.1111/dme.13416. Epub 2017 Jul 12.

Abstract

AIM

To develop models to estimate the direct medical costs associated with diabetes-related complications in the event year and in subsequent years.

METHODS

The public direct medical costs associated with 13 diabetes-related complications were estimated among a cohort of 128 353 people with diabetes over 5 years. Private direct medical costs were estimated from a cross-sectional survey among 1825 people with diabetes. We used panel data regression with fixed effects to investigate the impact of each complication on direct medical costs in the event year and subsequent years, adjusting for age and co-existing complications.

RESULTS

The expected annual public direct medical cost for the baseline case was US$1,521 (95% CI 1,518 to 1,525) or a 65-year-old person with diabetes without complications. A new lower limb ulcer was associated with the biggest increase, with a multiplier of 9.38 (95% CI 8.49 to 10.37). New end-stage renal disease and stroke increased the annual medical cost by 5.23 (95% CI 4.70 to 5.82) and 5.94 (95% CI 5.79 to 6.10) times, respectively. History of acute myocardial infarction, congestive heart failure, stroke, end-stage renal disease and lower limb ulcer increased the cost by 2-3 times. The expected annual private direct medical cost of the baseline case was US$187 (95% CI 135 to 258) for a 65-year-old man without complications. Heart disease, stroke, sight-threatening diabetic retinopathy and end-stage renal disease increased the private medical costs by 1.5 to 2.5 times.

CONCLUSIONS

Wide variations in direct medical cost in event year and subsequent years across different major complications were observed. Input of these data would be essential for economic evaluations of diabetes management programmes.

摘要

目的

建立模型以估算与糖尿病相关并发症在当年及后续年份的直接医疗成本。

方法

对超过 5 年期间的 128353 名糖尿病患者队列,估计了 13 种糖尿病相关并发症的公共直接医疗成本。通过横断面调查,对 1825 名糖尿病患者估计了私人直接医疗成本。我们使用面板数据固定效应回归,在调整年龄和并存并发症后,调查了每种并发症对当年及后续年份直接医疗成本的影响。

结果

基础病例的预期年度公共直接医疗成本为 1521 美元(95%CI 1518 至 1525)或无并发症的 65 岁糖尿病患者。新发下肢溃疡与最大增幅相关,乘数为 9.38(95%CI 8.49 至 10.37)。新发终末期肾病和中风使年度医疗费用分别增加了 5.23(95%CI 4.70 至 5.82)和 5.94(95%CI 5.79 至 6.10)倍。急性心肌梗死、充血性心力衰竭、中风、终末期肾病和下肢溃疡的病史使成本增加了 2-3 倍。基础病例的预期年度私人直接医疗成本为 187 美元(95%CI 135 至 258),适用于 65 岁无并发症的男性。心脏病、中风、威胁视力的糖尿病视网膜病变和终末期肾病使私人医疗费用增加了 1.5 至 2.5 倍。

结论

在当年及后续年份,不同主要并发症的直接医疗成本存在广泛差异。这些数据的投入对于糖尿病管理项目的经济评估至关重要。

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