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通过激光拉曼光谱法研究Pf1和fd病毒粒子中衣壳蛋白的结构

Structure of coat proteins in Pf1 and fd virions by laser raman spectroscopy.

作者信息

Thomas G, Murphy P

出版信息

Science. 1975 Jun 20;188(4194):1205-7. doi: 10.1126/science.1170637.

DOI:10.1126/science.1170637
PMID:1170637
Abstract

Rama spectra of filamentous bacterial viruses are dominated by scattering from vibrations of the protein capsomers. The amino acid compositions of coat proteins in Pfl and fd strains are recognized by their different side-chain vibrational frequencies. However, the conformationally sensitive amide frequencies indicate that Pfl and fd coat proteins have the same alpha-helicial secondary structures. Viral DNA backbones do not exhibit the A-type geometry.

摘要

丝状细菌病毒的拉曼光谱主要由蛋白质衣壳粒振动的散射所主导。Pfl和fd菌株中衣壳蛋白的氨基酸组成可通过其不同的侧链振动频率来识别。然而，构象敏感的酰胺频率表明Pfl和fd衣壳蛋白具有相同的α-螺旋二级结构。病毒DNA主链不呈现A型几何结构。

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Structure of coat proteins in Pf1 and fd virions by laser raman spectroscopy.通过激光拉曼光谱法研究Pf1和fd病毒粒子中衣壳蛋白的结构
Science. 1975 Jun 20;188(4194):1205-7. doi: 10.1126/science.1170637.
2
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