Meymaris E
Br J Anaesth. 1975 Feb;47 suppl:164-72.
The molecular mechanisms involved in the generation and conduction of nerve impulses are still matters for conjecture. The molecular models which have been developed to explain the structure of nerve membrane are reviewed. The chemical composition of the axolemma and how this compares with other membranes is discussed. Modern spectroscopic techniques allow the measurement of non-electrical dynamic changes that occur during nerve conduction. These indicate that the chemical components of nerve membrane are in a very fluid state. Detailed knowledge of the kinds of molecules involved is necessary to understand properly both nerve conduction and nerve block.
神经冲动的产生和传导所涉及的分子机制仍然是推测的话题。本文综述了为解释神经膜结构而建立的分子模型。讨论了轴膜的化学成分及其与其他膜的比较。现代光谱技术能够测量神经传导过程中发生的非电动态变化。这些变化表明神经膜的化学成分处于非常流体的状态。要正确理解神经传导和神经阻滞，就必须详细了解所涉及的分子种类。
