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幼年恒河猴外周神经脂质组成和神经传导的产后变化

Postnatal change in lipid composition and nerve conduction of peripheral nerves of young rhesus monkeys.

作者信息

Rana S V, Mehta S, Chopra J S

机构信息

Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

J Med Primatol. 1991 Aug;20(6):318-22.

PMID:1757976
Abstract

Body weight, motor and sensory nerve conduction velocities of fore and hind limbs, and lipid composition were measured sequentially in peripheral nerves of 15 rhesus monkeys. Initially measurements were made with monkeys six to eight months of age. There were significant increases in body weight, motor, and sensory nerve conduction and myelin marker lipids over a five months period, but no change was observed in free fatty acids, triglycerides, and esterified cholesterol. These results indicate that myelination continues at least for 11 to 13 months of postnatal age in rhesus monkeys.

摘要

对15只恒河猴的外周神经依次测量体重、前肢和后肢的运动及感觉神经传导速度,以及脂质成分。最初在6至8个月大的猴子身上进行测量。在五个月的时间里,体重、运动和感觉神经传导以及髓鞘标记脂质均有显著增加,但游离脂肪酸、甘油三酯和酯化胆固醇未见变化。这些结果表明,恒河猴出生后至少在11至13个月内髓鞘形成仍在继续。

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