[Antineoplastic activity of 5-fluorouracil upon transdermal adminstration using "Coletex" napkins].
作者信息
Vartanian L P, Oltarzhevskaia N D, Vershinina S F, Gornaeva G F, Pustovalov Iu I, Korovina M A
机构信息
Central Research Institute of Roentgeno-Radiology, Ministry of Health of the RF, St. Petersburg.
出版信息
Vopr Onkol. 2001;47(4):472-4.
PMID:11710293
Abstract
The paper presents data on the effect of 5-fluorouracil (5-FU)-impregnated Coletex napkins on rats and mice with transplantable subcutaneous tumors of different histological patterns: Pliss lymphosarcoma, Walker carcinosarcoma and Ehrlich carcinoma. Since the napkins showed antitumor activity it is suggested that they might find application in treating a number of oncological pathologies, particularly, skin lesions and ulcerated and necrotized tumors.
摘要
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