Chen E, Gedda U, Landau I
The Glaucoma and Oncology Services, Saint Erik's Eye Hospital, Karolinska Institutet, Stockholm, Sweden.
J Glaucoma. 2001 Oct;10(5):386-9. doi: 10.1097/00061198-200110000-00004.
To measure the thickness of the papillomacular bundle in glaucomatous eyes with good visual acuity and to evaluate the influence of an adjusted reference plane on the Heidelberg retinal tomography result.
The thickness of the papillomacular bundle was measured with optical coherence tomography in both eyes of eight patients with asymmetric glaucoma. The eye with less glaucomatous damage with normal visual field served as the control. The difference in the thickness of the papillomacular bundle between the control eye and the glaucomatous eye was used to correct the reference plane of Heidelberg retinal tomography.
The thickness of the papillomacular bundle in glaucomatous eyes was reduced (P = 0.00037) and was 33.9 +/- 16.5 microm thinner than control eyes. A corrected reference plane in Heidelberg retinal tomography caused an increased classification value (-0.683 +/- 0.164), implying that more glaucoma damage was detected after the correction. In one case the value was shifted from normal to glaucomatous after an adjustment of the reference plane.
The thickness of the papillomacular bundle is decreased in glaucomatous eyes, though these eyes have good visual acuity. Evaluation of glaucoma with Heidelberg retinal tomography using the standard reference plane may underestimate the glaucoma damage.
测量视力良好的青光眼患者视乳头黄斑束的厚度，并评估调整参考平面后对海德堡视网膜断层扫描结果的影响。
使用光学相干断层扫描测量8例不对称性青光眼患者双眼的视乳头黄斑束厚度。将视野正常且青光眼损害较轻的眼作为对照。用对照眼和青光眼患眼之间视乳头黄斑束厚度的差异来校正海德堡视网膜断层扫描的参考平面。
青光眼患眼视乳头黄斑束厚度降低（P = 0.00037），比对照眼薄33.9±16.5微米。海德堡视网膜断层扫描中校正后的参考平面使分类值增加（-0.683±0.164），这意味着校正后检测到更多的青光眼损害。在1例中，调整参考平面后，值从正常变为青光眼性。
尽管青光眼患者视力良好，但视乳头黄斑束厚度仍降低。使用标准参考平面的海德堡视网膜断层扫描评估青光眼可能会低估青光眼损害。
