Moe G K, Childers R W, Merideth J
Masonic Medical Research Laboratory, Utica, New York, USA.
Circulation. 1968 Jul;38(1):5-28. doi: 10.1161/01.cir.38.1.5.
Certain temporal patterns of A-V and V-A transmission in experimental preparations resemble phenomena attributed to "supernormal" conduction in the clinic. Detailed study of the properties of the A-V transmission system in such experiments reveals alternative explanations in which supernormality is clearly eliminated. By application of similar principles, supernormality can be eliminated as a factor in most if not all of the published examples. Three major categories can be discerned: (1) occult 2:1 A-V block, in which an idioventricular beat "retracts" an otherwise refractory barrier within the A-V node; (2) alternation between dissociated intranodal transmission pathways; and (3) "ventriculophasic" (vagal) depression of nodal conductivity.
实验制剂中A-V和V-A传导的某些时间模式类似于临床上归因于“超常”传导的现象。在此类实验中对A-V传导系统特性的详细研究揭示了其他解释,其中超常性被明确排除。通过应用类似原理,在大多数(如果不是全部)已发表的例子中,超常性都可以作为一个因素被排除。可以识别出三大类:(1)隐匿性2:1 A-V阻滞,其中室性自主搏动使A-V结内原本不应期的屏障“回缩”;(2)分离的结内传导途径之间的交替;(3)结传导性的“心室相性”(迷走神经)抑制。