Langston J W, Dorfman L J, Forno L S
Neurology. 1975 Jul;25(7):633-7. doi: 10.1212/wnl.25.7.633.
An elderly man presented with signs and symptoms indicating a rapidly progressive central and peripheral nervous system disease, which led to death within 3 months. The pathologic picture was that of a "paraneoplastic" encephalomyelitis and neuritis, but no cancer could be found. Supratentorial predilection for the limbic structures correlated well with an observed limbic dementia. Arguments favoring a direct toxic or metabolic effect of cancer as a cause for this syndrome was less convincing in view of this report.
一名老年男性出现了表明中枢和周围神经系统疾病快速进展的体征和症状，3个月内导致死亡。病理表现为“副肿瘤性”脑脊髓炎和神经炎，但未发现癌症。幕上结构对边缘系统的偏好与观察到的边缘叶痴呆密切相关。鉴于本报告，认为癌症的直接毒性或代谢作用是该综合征病因的观点不太令人信服。
