Martin G, Rand J
Companion Animal Sciences, School of Veterinary Science and Animal Production, The University of Queensland, Australia 4072.
J Feline Med Surg. 2000 Mar;2(1):3-17. doi: 10.1053/jfms.2000.0057.
When treating diabetic cats, the primary aim is to control clinical signs without causing clinical hypoglycaemia. Secondary goals are to maximise the chances of attaining diabetic remission and to minimise the risk of complications due to chronic hyperglycaemia. A treatment plan that is convenient for the owner is important for compliance. Underweight or overweight diabetic cats should be fed with the aim of normalising bodyweight. Current evidence suggests that non-obese diabetic cats can be fed ad libitum. The oral hypoglycaemic drug glipizide is well established as a treatment for about a third of diabetic cats, which have residual beta cell function. Preliminary studies on other oral agents such as vanadium salts, metformin, and troglitazone indicate a potential use in some diabetic cats. Insulin treatment remains the treatment of choice for the majority of diabetic cats. Choice of insulin, dose rates and monitoring of treatment are discussed.
治疗糖尿病猫时，主要目标是控制临床症状而不引起临床低血糖。次要目标是最大程度提高实现糖尿病缓解的几率，并将慢性高血糖导致的并发症风险降至最低。对主人方便的治疗方案对于依从性很重要。体重过轻或超重的糖尿病猫应以使体重正常化为目标进行喂养。目前的证据表明，非肥胖型糖尿病猫可以自由采食。口服降糖药格列吡嗪作为约三分之一具有残余β细胞功能的糖尿病猫的治疗药物已得到充分认可。对钒盐、二甲双胍和曲格列酮等其他口服药物的初步研究表明，它们在某些糖尿病猫中具有潜在用途。胰岛素治疗仍然是大多数糖尿病猫的首选治疗方法。文中讨论了胰岛素的选择、剂量率和治疗监测。
