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人甲状旁腺自体移植:通过血浆甲状旁腺激素放射免疫测定法证实其功能

Human parathyroid autotransplantation: proved function by radioimmunoassay of plasma parathyroid hormone.

作者信息

Hickey R C, Samaan N A

出版信息

Arch Surg. 1975 Aug;110(8):892-5. doi: 10.1001/archsurg.1975.01360140036007.

DOI:10.1001/archsurg.1975.01360140036007
PMID:1171674
Abstract

The possibility of transplanting parathyroid gland fragments into accessible muscle as functioning autografts in the human being has been supported but unproved. During operations in the thyrocervical area, the parathyroid glands frequently are removed, either intentionally or inadvertently. We have had occasion to transplant slices of parathyroid glands in five instances; four parathyroid glands were proved to be normal, and a benign adenoma appeared in the fifth. The parathyroid gland was positioned in a muscular bed in the patient's forearm. Plasma parathyroid hormone (PTH) measurements by radioimmunoassay were made from the implant venous effluent. The venous outflow from the contralateral arm was used for control. We have concluded that parathyroid tissue can be transplanted, does function, and might be capable of providing calcium homeostasis.

摘要

将甲状旁腺碎片移植到人体易于触及的肌肉中作为有功能的自体移植,这种可能性虽有依据但尚未得到证实。在甲状腺颈部区域手术期间,甲状旁腺常常被有意或无意地摘除。我们有机会进行了5例甲状旁腺切片移植;其中4个甲状旁腺经证实是正常的,第5个是良性腺瘤。甲状旁腺被置于患者前臂的肌肉床中。通过放射免疫分析法对植入物静脉流出液进行血浆甲状旁腺激素(PTH)测量。对侧手臂的静脉流出液用作对照。我们得出结论,甲状旁腺组织能够移植、发挥功能,并且可能能够维持钙稳态。

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1
Human parathyroid autotransplantation: proved function by radioimmunoassay of plasma parathyroid hormone.人甲状旁腺自体移植:通过血浆甲状旁腺激素放射免疫测定法证实其功能
Arch Surg. 1975 Aug;110(8):892-5. doi: 10.1001/archsurg.1975.01360140036007.
2
Clinical experience of parathyroid autotransplantation.甲状旁腺自体移植的临床经验
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Parathyroid autotransplantation at a novel site for better evaluation of the grafted gland function: study protocol for a prospective, randomized controlled trial.甲状旁腺在新部位进行自体移植以更好地评估移植腺体功能:一项前瞻性随机对照试验的研究方案
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Autotransplantation of parathyroid glands into subcutaneous forearm tissue for renal hyperparathyroidism.将甲状旁腺自体移植至前臂皮下组织治疗肾性甲状旁腺功能亢进症。
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Experimental cryopreservation and autotransplantation of parathyroid glands: technique and demonstration of function.甲状旁腺的实验性冷冻保存与自体移植:技术与功能展示
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引用本文的文献

1
Preservation of parathyroid glands during thyroid and neck surgery.甲状腺及颈部手术中甲状旁腺的保护。
Front Endocrinol (Lausanne). 2023 May 31;14:1173950. doi: 10.3389/fendo.2023.1173950. eCollection 2023.
2
Parathyroid autotransplantation at a novel site for better evaluation of the grafted gland function: study protocol for a prospective, randomized controlled trial.甲状旁腺在新部位进行自体移植以更好地评估移植腺体功能:一项前瞻性随机对照试验的研究方案
Trials. 2019 Jan 31;20(1):96. doi: 10.1186/s13063-019-3195-9.
3
Short and long-term impact of parathyroid autotransplantation on parathyroid function after total thyroidectomy.
甲状旁腺自体移植对全甲状腺切除术后甲状旁腺功能的短期和长期影响。
Gland Surg. 2017 Dec;6(Suppl 1):S75-S85. doi: 10.21037/gs.2017.09.15.
4
Parathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: A Simple and Effective Way to Avoid Hypoparathyroidism.甲状腺切除术中将甲状旁腺重新植入前臂皮下组织:一种避免甲状旁腺功能减退的简单有效方法。
World J Surg. 2015 Aug;39(8):1936-42. doi: 10.1007/s00268-015-3070-0.
5
Autografts of normal and hyperplastic human parathyroid: experience in eleven patients with immunoassay monitoring of function in seven.正常及增生性人甲状旁腺自体移植:11例患者的经验,其中7例进行了功能的免疫测定监测
World J Surg. 1980;4(2):209-21. doi: 10.1007/BF02393579.
6
Treatment of secondary hyperparathyroidism in patients with chronic renal failure by total parathyroidectomy and parathyroid autograft.通过甲状旁腺全切除术和甲状旁腺自体移植治疗慢性肾衰竭患者的继发性甲状旁腺功能亢进。
Ann Surg. 1981 Jun;193(6):777-93. doi: 10.1097/00000658-198106000-00014.
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Medullary carcinoma of the thyroid.甲状腺髓样癌
World J Surg. 1981 Jan;5(1):27-32. doi: 10.1007/BF01657830.
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[Cryopreservation of human parathyroid tissue (author's transl)].人甲状旁腺组织的冷冻保存(作者译)
Langenbecks Arch Chir. 1980;353(3):183-91. doi: 10.1007/BF01261962.
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Ann Surg. 1983 Jan;197(1):7-16.
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Total thyroidectomy in irradiated patients. A twenty-year experience in 206 patients.放疗后患者的全甲状腺切除术。206例患者的20年经验。
Ann Surg. 1985 Sep;202(3):356-60. doi: 10.1097/00000658-198509000-00013.