Hatch C D, Lund B C, Perry P J
Clinical and Administrative Division, College of Pharmacy, University of Iowa, Iowa City 52242-1112, USA.
Pharmacotherapy. 2001 Aug;21(8):1003-6. doi: 10.1592/phco.21.11.1003.34528.
Neuroleptic malignant syndrome (NMS) is an uncommon but potentially life-threatening adverse effect associated with conventional antipsychotic agents. The syndrome is characterized by muscular rigidity, hyperpyrexia, altered consciousness, and autonomic dysfunction. Few cases of quetiapine-induced NMS have been reported. A 54-year-old man was unsuccessfully challenged with quetiapine after conventional antipsychotic-induced NMS.
抗精神病药恶性综合征（NMS）是一种与传统抗精神病药物相关的罕见但可能危及生命的不良反应。该综合征的特征为肌肉强直、高热、意识改变及自主神经功能障碍。喹硫平诱发NMS的病例报道较少。一名54岁男性在传统抗精神病药物诱发NMS后，使用喹硫平激发试验未成功。
