Styf J R, Hutchinson K, Carlsson S G, Hargens A R
Life Science Division, NASA Ames Research Center, Moffet Field, CA, USA.
Psychosom Med. 2001 Nov-Dec;63(6):862-4. doi: 10.1097/00006842-200111000-00002.
The objective of this study was to develop a ground-based model for spinal adaptation to microgravity and to study the effects of spinal adaptation on depression, mood state, and pain intensity.
We investigated back pain, mood state, and depression in six subjects, all of whom were exposed to microgravity, simulated by two forms of bed rest, for 3 days. One form consisted of bed rest with 6 degrees of head-down tilt and balanced traction, and the other consisted of horizontal bed rest. Subjects had a 2-week period of recovery between the studies. The effects of bed rest on pain intensity in the lower back, depression, and mood state were investigated.
Subjects experienced significantly more intense lower back pain, lower hemisphere abdominal pain, headache, and leg pain during head-down tilt bed rest. They had higher scores on the Beck Depression Inventory (ie, were more depressed) and significantly lower scores on the activity scale of the Bond-Lader questionnaire.
Bed rest with 6 degrees of head-down tilt may be a better experimental model than horizontal bed rest for inducing the pain and psychosomatic reactions experienced in microgravity. Head-down tilt with balanced traction may be a useful method to induce low back pain, mood changes, and altered self-rated activity level in bed rest studies.
本研究的目的是建立一个模拟脊柱适应微重力环境的地面模型，并研究脊柱适应对抑郁、情绪状态和疼痛强度的影响。
我们对6名受试者进行了背痛、情绪状态和抑郁情况的调查，所有受试者均通过两种形式的卧床休息模拟微重力环境，持续3天。一种形式是头部向下倾斜6度并伴有平衡牵引的卧床休息，另一种是水平卧床休息。受试者在两次研究之间有2周的恢复期。研究了卧床休息对下背部疼痛强度、抑郁和情绪状态的影响。
在头部向下倾斜的卧床休息期间，受试者经历了更强烈的下背部疼痛、下腹部疼痛、头痛和腿部疼痛。他们在贝克抑郁量表上的得分更高（即更抑郁），在邦德-莱德问卷活动量表上的得分显著更低。
对于诱发微重力环境下所经历的疼痛和身心反应而言，6度头部向下倾斜的卧床休息可能是比水平卧床休息更好的实验模型。在卧床休息研究中，头部向下倾斜并伴有平衡牵引可能是诱发下背部疼痛、情绪变化和自我评定活动水平改变的一种有用方法。
