de Wert G
Universiteit Maastricht, Instituut voor Gezondheidsethiek, Postbus 616, 6200 MD Maastricht.
Ned Tijdschr Geneeskd. 2001 Nov 3;145(44):2109-11.
Human embryos can be conceived by cell nuclear transfer in order to isolate human embryonic stem cells (hES cells) for research into autologous cell therapy (therapeutic cloning). However, this technique broaches the major ethical problem concerning the instrumental use of human preimplantation embryos. From the viewpoint of subsidiarity, it is argued that various potential alternatives for therapeutic cloning should first be investigated further. The question as to whether therapeutic cloning should be allowed only becomes apparent when research with surplus embryos obtained in the course of in-vitro fertilization suggests that usable transplants can be obtained in vitro from hES cells, and when the potential alternatives for therapeutic cloning are either less promising or need more time for development than is currently expected.
为了分离人类胚胎干细胞(hES细胞)用于自体细胞治疗研究(治疗性克隆),可以通过细胞核移植来培育人类胚胎。然而,这项技术引发了关于将人类植入前胚胎用作工具的重大伦理问题。从辅助性原则的角度来看,有人认为应该首先进一步研究治疗性克隆的各种潜在替代方法。只有当对体外受精过程中获得的多余胚胎进行的研究表明可以从hES细胞中体外获得可用的移植组织,并且治疗性克隆的潜在替代方法要么前景不那么乐观,要么需要比目前预期更长的时间来发展时,治疗性克隆是否应该被允许的问题才会变得明显。