一种抗感染联合用药的评估。甲氧苄啶-磺胺甲恶唑（复方新诺明，抗菌优）。

Evaluation of an anti-infective combination. Trimethoprim-sulfamethoxazole (Bactrim, Septra).

作者信息

Schiffman D O

出版信息

JAMA. 1975 Feb 10;231(6):635-7.

Abstract

Trimethoprim and sulfamethoxazole, combined in a synthetic anti-infective preparation, act synergistically to inhibit the growth of certain microorganisms. This combination is effective orally in acute and chronic urinary tract infections. It also has been used successfully to treat other infectious conditions, including bacterial upper respiratory tract infections, ear infections, skin and soft-tissue infections, septicemias, acute and subacute bacterial endocarditis, enteric fever, brucellosis, prostatitis, and gonorrhea. It is well tolerated by most patients.

摘要

甲氧苄啶和磺胺甲恶唑联合制成一种合成抗感染制剂，具有协同作用，可抑制某些微生物的生长。这种组合对急性和慢性尿路感染口服有效。它也已成功用于治疗其他感染性疾病，包括细菌性上呼吸道感染、耳部感染、皮肤和软组织感染、败血症、急性和亚急性细菌性心内膜炎、伤寒、布鲁氏菌病、前列腺炎和淋病。大多数患者对其耐受性良好。