Henderson I R, Lam A C
Division of Immunity and Infection, The Medical School, University of Birmingham, Edgbaston, B15 2TT., Birmingham, UK.
Trends Microbiol. 2001 Dec;9(12):573-8. doi: 10.1016/s0966-842x(01)02234-x.
Gram-negative bacteria secrete a variety of proteins to the cell surface and beyond, a process with many inherent difficulties. An exceptionally widespread answer to these problems is the type V (or autotransporter) secretion pathway. By exploiting the data made available by bacterial genome sequencing, we have discovered that the previously described polymorphic proteins of Chlamydia spp. resemble members of the autotransporter family, and we suggest that they follow the same secretion pathway.
革兰氏阴性菌会向细胞表面及细胞外分泌多种蛋白质，这一过程存在许多内在困难。针对这些问题，一种极为普遍的解决方式是V型（或自转运体）分泌途径。通过利用细菌基因组测序所提供的数据，我们发现衣原体属先前描述的多态性蛋白类似于自转运体家族的成员，并且我们认为它们遵循相同的分泌途径。
