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[通过植入式导管-端口系统使用盐水注射磁共振成像评估腹腔化疗期间腹腔内药物分布]

[Assessment of intraperitoneal drug distribution during intraperitoneal chemotherapy using saline-injected MR imaging through an implanted catheter-port system].

作者信息

Obuchi M, Shimizu A, Fujiwara T, Sugimoto H, Honda M, Kubota H, Yamamoto W, Kinebuchi Y

机构信息

Dept. of Radiology, Dept. of Obstetrics and Gynecology, Showa University Fujigaoka Hospital.

出版信息

Gan To Kagaku Ryoho. 2001 Nov;28(12):1891-5.

PMID:11729482
Abstract

Intraperitoneal saline-injected MR imaging through an implanted catheter-port system (saline-MRI) was conducted in 7 patients with ovarian tumor after surgical removal of the primary tumor. Two types of T2 weighted coronal images of the abdomen were obtained after saline injection through the implanted catheter-port system. One uses long TE (about 1000 msec) with fat-saturation and thick slices (100 mm thickness) to depict the injected saline alone. The other uses medium TE (about 100 msec) without fat-saturation and thin slices (10 mm thickness) to depict both intraperitoneal saline and abdominal structures. Saline sequentially fills the Douglas pouch, paracolic gutter, Morison's pouch and subphrenic space in most patients. The relation between injected saline and abdominal structures was seen well on T2-weighted images using medium TE. Adhesions of the peritoneum were well demonstrated. In one patient, a catheter perforation to the bowel loop was diagnosed, because the small bowel loop was immediately filled with injected saline. Saline-MRI can be used to depict intraperitoneal drug distribution during intraperitoneal chemotherapy and can diagnose complications related to intraperitoneal chemotherapy.

摘要

7例卵巢肿瘤患者在手术切除原发肿瘤后,通过植入的导管-端口系统进行了腹腔内注射生理盐水的磁共振成像(生理盐水-MRI)。通过植入的导管-端口系统注射生理盐水后,获得了两种类型的腹部T2加权冠状位图像。一种使用长TE(约1000毫秒)并带有脂肪抑制和厚层(100毫米厚度),仅用于描绘注入的生理盐水。另一种使用中等TE(约100毫秒)且无脂肪抑制和薄层(10毫米厚度),用于描绘腹腔内生理盐水和腹部结构。在大多数患者中,生理盐水依次填充道格拉斯窝、结肠旁沟、莫里森窝和膈下间隙。使用中等TE的T2加权图像上可以很好地观察到注入的生理盐水与腹部结构之间的关系。腹膜粘连得到了很好的显示。在1例患者中,诊断出导管穿入肠袢,因为注入的生理盐水立即充满了小肠袢。生理盐水-MRI可用于描绘腹腔内化疗期间腹腔内药物分布,并可诊断与腹腔内化疗相关的并发症。

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Gan To Kagaku Ryoho. 2001 Nov;28(12):1891-5.
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