Ikeda H, Kitamura A, Uehara M, Tobita T, Ohba S, Nonaka M, Fujisawa A, Inokuchi T
Second Dept. of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry.
Gan To Kagaku Ryoho. 2001 Nov;28(12):1929-31.
A 73-year-old male with squamous cell carcinoma of the oral floor (T1N0M0), who had not consented to radical treatment was treated with UFT by oral administration alone. After commencement of the administration, tumor remission was observed at 2 weeks and disappeared clinically at 8 weeks. The total period of oral administration of UFT was twenty-three months, and the total dose was 186.5 g as tegafur. Major adverse effects were pigmentation of hands and liver dysfunction. He remains under observation, and there is no evidence of tumor recurrence.
一名73岁男性，患有口腔底部鳞状细胞癌（T1N0M0），未同意接受根治性治疗，仅通过口服优福定进行治疗。给药开始后，2周时观察到肿瘤缓解，8周时临床消失。优福定口服总疗程为23个月，替加氟总剂量为186.5g。主要不良反应为手部色素沉着和肝功能障碍。他仍在接受观察，目前没有肿瘤复发的迹象。
