Kasai N, Mutoh Y
Dept. of Dentistry and Oral Surgery, Niigata Rosai Hospital.
Gan To Kagaku Ryoho. 1999 Feb;26(3):373-6.
We report a case of squamous cell carcinoma of the lower lip showing an excellent response to chemotherapy with UFT. A 68-year-old woman with a painless swelling of her lower lip was refereed to our service. This tumor was 19 x 18 mm with cauliflower surface, and induration was noted around the mass. The pathological diagnosis was squamous cell carcinoma of well-differentiated type. After chemotherapy with UFT (400 mg/day), the tumor became flat. It was then removed with a 7 mm-safety margin and the lower lip was reconstructed with an Abbe-Estlandar flap from the upper lip. Post-operative histological findings indicated a complete response. Wound healing was uneventful, and there has been no evidence of recurrence for these 6 months after the operation. This case is still under observation.
我们报告一例下唇鳞状细胞癌对优福定（UFT）化疗反应良好的病例。一名68岁女性因下唇无痛性肿胀转诊至我院。该肿瘤大小为19×18毫米，表面呈菜花状，肿物周围有硬结。病理诊断为高分化型鳞状细胞癌。经优福定（400毫克/天）化疗后，肿瘤变平。随后以7毫米的安全切缘将肿瘤切除，用上唇的阿贝-埃斯特兰德皮瓣重建下唇。术后组织学检查结果显示完全缓解。伤口愈合顺利，术后6个月无复发迹象。该病例仍在观察中。
