Yang S S, Chiou Y H, Lin C Y, Cher T W, Yu T J, Lin A T, Chen S C, Lai M K
Department of Urology, En Chu Kong Hospital, Taiwan.
Acta Paediatr Taiwan. 2001 Sep-Oct;42(5):271-7.
The treatment guideline of enuresis suggested by the study group of enuresis in Taiwan is reported. Medical consultation and treatment of enuresis are recommended at the age of 5 and 6 years respectively. Evaluation of the enuretic children includes history taking, physical examination and laboratory investigations. A checklist is provided for quick evaluation in busy clinics. Urinalysis, urine specific gravity and office ultrasonography are essential tests. An algorithm of treatment of monosymptomatic enuresis is constructed. The two main options of treatment are behavioral modification with alarm system and pharmacotherapy with desmopressin or imipramine. Imipramine is recommended as one of the treatment options because of its relative safety in Taiwan. However the potential toxicity and mortality of imipramine is highlighted and warned. The responses to treatment are evaluated after a period of treatment for 1 to 3 months. Further evaluation and individualized treatment is suggested for poor responders.
报道了台湾遗尿症研究小组提出的遗尿症治疗指南。建议分别在5岁和6岁时进行遗尿症的医学咨询和治疗。对遗尿儿童的评估包括病史采集、体格检查和实验室检查。提供了一份清单以便在繁忙的诊所进行快速评估。尿常规、尿比重和门诊超声检查是必不可少的检查。构建了单症状性遗尿症的治疗算法。治疗的两个主要选择是使用警报系统进行行为矫正以及使用去氨加压素或丙咪嗪进行药物治疗。由于丙咪嗪在台湾相对安全,因此被推荐为治疗选择之一。然而,强调并警告了丙咪嗪的潜在毒性和死亡率。在治疗1至3个月后评估治疗反应。对于反应不佳者,建议进一步评估和个体化治疗。