Marques Pereira M L, Katz L J
Department of Ophthalmology, University of Iowa Hospital, Ames, Iowa, USA.
Am J Ophthalmol. 2001 Dec;132(6):928-9. doi: 10.1016/s0002-9394(01)01143-6.
To report a case of delayed choroidal detachment after treatment with topical latanoprost.
Interventional case report. Five years after trabeculectomy in a 91-year-old female, a Holmium laser thermal sclerostomy was performed, and a year later, the patient was started on latanoprost.005% every 24 hours and hydrochloride dorzolamide 2% three times daily.
Choroidal detachments developed 2.5 years after the sclerostomy; they resolved after discontinuation of the latanoprost and hydrochloride dorzolamide. Subsequently, the patient inadvertently restarted latanoprost. Again, the latanoprost was stopped, with resolution of the choroidal detachments.
Topical latanoprost may lead to choroidal detachments and hypotony.
报告1例使用局部拉坦前列素治疗后发生延迟性脉络膜脱离的病例。
介入性病例报告。1例91岁女性小梁切除术后5年，接受钬激光热巩膜造口术，1年后，患者开始每24小时使用0.005%拉坦前列素，并每日3次使用2%多佐胺盐酸盐。
巩膜造口术后2.5年发生脉络膜脱离；停用拉坦前列素和多佐胺盐酸盐后脱离消退。随后，患者无意中重新开始使用拉坦前列素。脉络膜脱离再次出现，再次停用拉坦前列素后脱离消退。
局部使用拉坦前列素可能导致脉络膜脱离和低眼压。
