Pathanapitoon Kessara, Kunavisarut Paradee
Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
J Med Assoc Thai. 2005 Aug;88(8):1134-6.
To report three cases of delayed choroidal detachment after treatment with topical prostaglandin analogs.
Intervention three case reports. Four eyes of three patients with chronic angle closure glaucoma developed choroidal detachment after using topical prostaglandin analogs.
Three patients with chronic angle closure glaucoma developed chroidal detachment in one week, three weeks and two years after using travoprost, bimatoprost and latanoprost respectively. All of them resolved after discontinuation of these medications. All of the eyes that developed chroidal detachment were pseudophakic.
Travoprost, bimatoprost and latanoprost may lead to choroidal detachment and hypotony. Pseudophakic patients may be at high risk of the development of chroidal detachment. Topical prostaglandin analogs should be used cautiously in these patients.
报告三例局部应用前列腺素类似物治疗后发生延迟性脉络膜脱离的病例。
干预性病例报告。三名慢性闭角型青光眼患者的四只眼在使用局部前列腺素类似物后发生脉络膜脱离。
三名慢性闭角型青光眼患者分别在使用曲伏前列素、比马前列素和拉坦前列素后一周、三周和两年发生脉络膜脱离。停用这些药物后均恢复。所有发生脉络膜脱离的眼均为人工晶状体眼。
曲伏前列素、比马前列素和拉坦前列素可能导致脉络膜脱离和低眼压。人工晶状体眼患者发生脉络膜脱离的风险可能较高。在这些患者中应谨慎使用局部前列腺素类似物。
