Kraus Dennis H
Department of Otolaryngology, Cornell University Medical Center, 1275 York Avenue, New York, NY 10021, USA.
Curr Oncol Rep. 2002 Jan;4(1):68-75. doi: 10.1007/s11912-002-0050-y.
Sarcomas of the head and neck are extremely rare, accounting for less than 1% of all neoplasms of the head and neck. These sarcomas arise in both soft tissues and bone and thus cannot be treated by a single approach. The clinical behavior of these tumors varies considerably. Patients with low-grade lesions are prone to local recurrence, whereas those with high-grade lesions develop both local recurrence and disseminated disease. An additional complicating factor is the multiple sites in which sarcomas may arise in the head and neck. All of these factors make it difficult to ascertain the optimal treatment approach for sarcomas. This article reviews the current literature (as well as the author's own experience) and provides a general treatment guideline for sarcomas of the head and neck.
头颈部肉瘤极为罕见,占所有头颈部肿瘤的比例不到1%。这些肉瘤可发生于软组织和骨骼,因此无法采用单一方法进行治疗。这些肿瘤的临床行为差异很大。低级别病变的患者容易出现局部复发,而高级别病变的患者则会出现局部复发和播散性疾病。另一个复杂因素是头颈部肉瘤可能出现的多个部位。所有这些因素都使得难以确定肉瘤的最佳治疗方法。本文回顾了当前文献(以及作者自身的经验),并提供了头颈部肉瘤的一般治疗指南。