垂体无功能性嫌色细胞腺瘤中分泌颗粒直径与正常促甲状腺激素细胞分泌颗粒直径的相关性。
Correlation of diameters of secretory granules in clinically non-functioning chromophobe adenomas of the pituitary with those of normal thyrotrophs.
作者信息
Gray A B, Doniach I, Leigh P N
出版信息
Acta Endocrinol (Copenh). 1975 Jul;79(3):417-20. doi: 10.1530/acta.0.0790417.
Diameters of secretory granules in thyrotrophs in gonadotrophs were measured in electron micrographs of operation specimens of 4 pituitary glands and of the secretory granules in operation specimens of 10 clinically non-functioning chromophobe adenomas. The mean diameter of the thyrotroph granules was 137 plus or minus 26 nm, of the gonadotrophs 204 plus or minus 38 nm, of 9 of the adenomas 141 plus or minus 20 nm and of the remaining adenoma 248 plus or minus 67 nm. The significance of the close correlation in granule size in most of the adenomas with that of thyrotrophin granules is discussed briefly.
在4个垂体手术标本的电子显微照片中，测量了促甲状腺激素细胞和促性腺激素细胞中分泌颗粒的直径，以及10例临床无功能嫌色细胞瘤手术标本中分泌颗粒的直径。促甲状腺激素细胞颗粒的平均直径为137±26 nm，促性腺激素细胞颗粒的平均直径为204± 38 nm，9例腺瘤的平均直径为141±20 nm，其余腺瘤的平均直径为248±67 nm。简要讨论了大多数腺瘤中颗粒大小与促甲状腺激素颗粒大小密切相关的意义。
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